Apheresis Procedures in Our Clinics

Hemoperfusion

Hemoperfusion is used for severe inflammation, sepsis, medication overdoses, poisoning, severe kidney disease, liver failure, rhabdomyolysis, severe acute pancreatitis, and hyperlipidemia. Unlike DFPP, where plasma is passed through a fractionation filter, hemoperfusion does not separate plasma; instead, the whole blood flows through a specialized adsorption cartridge with multiple functions.

Hemoperfusion effectively removes both endogenous and exogenous molecules, including inflammatory mediators, cytokines, bilirubin, metabolic toxins, overdosed or residual medications, poisons, accumulated β2-microglobulin, excess parathyroid hormone, leptin, and other protein-bound toxins, as well as triglycerides, cholesterol in severe pancreatitis, and myoglobin.

Double Filtration Plasmapheresis (DFPP)

Double Filtration Plasmapheresis (DFPP) is a modern, targeted blood purification therapy with scientifically proven effectiveness in the treatment of numerous medical conditions. It involves the selective removal of harmful substances — such as autoantibodies, inflammatory mediators, lipoproteins, and toxins — while preserving essential plasma components. DFPP is an internationally recognized medical therapy, included in major evidence-based treatment guidelines such as: the American Society for Apheresis (ASFA) guidelines, the German Standard der Therapeutischen Apherese, the clinical standards of the Japanese Society for Apheresis.

DFPP is a closed-loop process. Thanks to our state-of-the-art technology, only a very small volume of blood (approximately 250 ml) is processed in the device at any time. This ensures that you do not experience a deficiency of essential blood components or an electrolyte imbalance. At the end of the treatment, you lose only about 150 ml of concentrated pathological plasma, which can be sent to a laboratory for diagnostic analysis upon request.

Because we use filters to separate plasma and red blood cells, a high blood flow is not required. Therefore, in most cases, we can use peripheral veins in the forearm, similar to an intravenous infusion.

Thanks to advanced technology, there is no risk of infection, as the blood does not come into direct contact with any device parts. It flows exclusively through sterile single-use kits and filters, which can be unpacked in front of you before the treatment begins, if desired.

The information provided is for general informational purposes only and does not replace individual medical advice or treatment.

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